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PUBLICATION, JANUARY, 2014. The Bioscientist. Vol. 2

The Bioscientist Vol. 2 (1): 103-109, January 2014.
Available online at http://www.bioscientistjournal.com
Enemchukwu et al.,2014 Page 65

Phytochemical Screening and Biochemical Effects of Aqueous Seed Extract of
Xylopiaaethiopica (Uda) on SelectedHaematological Indices in Male Wistar
Albino rats.

1*Enemchukwu,B.N., 1Erimujor, S.O. and 2Ubaoji,K.I

1Department of Science Laboratory Technology, Akanu Ibiam Federal

Polytechnic,Unwana, P.M.B.1007,Afikpo, Ebonyi State, Nigeria

2Dept. of Applied Biochemistry, Nnamdi Azikiwe University, Awka, Nigeria

*Corresponding author email: achylesma@yahoo.com

ABSTRACT (Download PDF )

The biochemical effects of aqueous seed extract of Xylopia aethiopica (uda) were determined on selected haematological indices of male Wistar albino rats using standard methods. Twenty five adult male rats were selected according to their weights and were divided into five groups designated A,B,C,D and E of five animals per group. Group A (control) received distilled water (1.0mL/kg body weight) whereas Groups B,C,D and E organisms were treated with 1.0mg/kg body weight, 2.0mg/kg body weight, 3.0mg/kg body weight and 4.0mg/kg body weight of extract respectively. The administration of the extract was carried out twice daily for 14 days after which the animals were anaesthesized and blood samples were collected 24 hours after the last administration through cardiac puncture and haematological studies carried out. The result revealed highest values of packed cell volume and invariably highest haemoglobin concentration (Hb) in Group E animals compared to the other groups. Phytochemical screening revealed the presence of volatile oils, tannins, flavonoids and saponins while phytosterols, glycosides while alkaloids were absent. From the findings in this prospective study, Xylopia aethiopica seed extract has useful pharmacological bioactive compounds and as such could be used as tonic in traditional medicine and as immune booster.

Keywords: Haematological, indices, experimental, organisms, Wistar, rats.

© 2013. Journal of Faculty of Biosciences, Nnamdi Azikiwe University,

P. M. B. 5025 Awka, Nigeria.

email: thebioscientist@unizik.edu.ng

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