HUMAN PREDISPOSITION TO OBESITY
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Abstract
The prevalence of obesity among people in our society is worrisome and many individuals are currently struggling for survival under the complications of obesity. The study examined the factors that predispose humans to obesity. Obesity is a condition characterized by the excessive accumulation of fat in adipose tissue when compared with normal quantity expected for a given weight, age and height. Epidemiologically, it occurs at any time in life, in both sexes and different social classes. The study showed that humans are predisposed to obesity by genetic, endocrine, dietary fat, sedentary life-style, psychological and antibiotic factors. Genes affect a number of weight related processes in the body and defects in them impair satiety and mechanisms of energy intake, energy expenditure and partitioning of nutrients between fat and lean tissues. Obese humans have high plasma leptin concentrations related to the size of adipose tissues without inducing the expected responses which suggests resistance to endogenous leptin. Some of the complications of obesity include mechanical disability, metabolic disorders, cardiovascular disorder, respiratory problems, and reduction in life expectancy. Our recommendations include periodic assessment of individual’s nutritional status by determining the body mass index; recognizing and controlling environmental cues; and engaging in physical activities.
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